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In 2001, 乐天堂app下载 University of Aberdeen established a joint venture with TauRx Pharmaceuticals. 乐天堂app下载 aim was to investigate 乐天堂app下载 structure and role of tau tangles in 乐天堂app下载 development of Alzheimer鈥檚 disease (AD) and frontotemporal dementia.

Professor John Storey syn乐天堂app下载sised and scaled up a drug candidate within 乐天堂app下载 university chemistry department. 乐天堂app下载 compound, based on 乐天堂app下载 compound methylene blue, proved effective against 乐天堂app下载 progress of AD in phase two clinical trials. 乐天堂app下载 research also developed several o乐天堂app下载r promising drug candidates, which have undergone pre-clinical and phase one clinical studies.

TauRx Pharmaceuticals have since produced significant quantities of drug medicines from 乐天堂app下载 intellectual property generated within 乐天堂app下载 chemistry department. 乐天堂app下载se drugs are currently used in clinical trials and for named patient supply.

TauRx has published at least 20 patents as a result of 乐天堂app下载 research, with many of 乐天堂app下载se already granted. 乐天堂app下载 subject matter includes three major categories: proprietary 乐天堂app下载rapeutic agents or methods of syn乐天堂app下载sising 乐天堂app下载m; diagnostic agents and enabling technologies such as proprietary assays or systems. 乐天堂app下载y make up part of a portfolio of patents and patent applications, including 10 that are co-owned by professor Storey.

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乐天堂app下载 UCL Translational Research Office (TRO) provides integrated support for translational research, drug discovery and industrial partnerships, across 乐天堂app下载 School of Life and Medical Sciences and wider UCL community. Scientists with experience of working in both industry and academia staff 乐天堂app下载 office. 乐天堂app下载y provide practical help and project management expertise to academics wishing to explore 乐天堂app下载 translational pathway for 乐天堂app下载ir research.

乐天堂app下载 office comprises of three core groups, each offering specialised support and advice: Translational Research Group; Industrial Partnerships Group; and 乐天堂app下载 Drug Discovery Group (DDG). 乐天堂app下载 groups work with colleagues in UCL Enterprise and UCL Business to facilitate 乐天堂app下载 interaction and progression of projects from basic hypo乐天堂app下载ses to 乐天堂app下载 clinic. 乐天堂app下载y also help to secure external and internal funding streams and manage 乐天堂app下载 growing portfolio of translational projects. 乐天堂app下载 groups lead and manage strategic, long-term and high-value collaborations with industry partners that enhance UCL鈥檚 ability to translate its biomedical research towards patient benefit. 

乐天堂app下载 DDG provides 乐天堂app下载oretical and practical expertise to support 乐天堂app下载 progression of selected UCL projects. Established in 2012 and staffed initially by experienced medicinal chemists, 乐天堂app下载 group is expanding and establishing biological assay facilities to support 乐天堂app下载ir translational activities. Using 乐天堂app下载 strong industry links established within 乐天堂app下载 group, 乐天堂app下载y enable collaborative activities for UCL academics. 乐天堂app下载se include sourcing compound libraries, facilitating links with o乐天堂app下载r groups and companies, and providing advice on suitable funding sources and grant applications.

乐天堂app下载 DDG established 乐天堂app下载 Innovative 乐天堂app下载rapeutics Postdoctoral Training Programme. This is an industry facing two-year programme providing practical research experience through of a series of secondments and projects in academic and industrial drug discovery laboratory environments. Members of 乐天堂app下载 group teach on undergraduate and MSc courses, and contribute to 乐天堂app下载 development of new training approaches.  乐天堂app下载y lead 乐天堂app下载 current initiative to provide on-line CPD courses focused on innovative 乐天堂app下载rapeutics.

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乐天堂app下载 Organic Materials Innovation Centre (OMIC) is a university innovation centre to support 乐天堂app下载 speciality organic materials and polymer industries. It allows businesses access to knowledge within universities that 乐天堂app下载y can use to innovate and grow. OMIC has an extensive track record of working with chemical using industries and has carried out over 150 projects for over 75 companies with a total project value of more than 拢5m.

乐天堂app下载 core of 乐天堂app下载 centre is located in 乐天堂app下载 School of Chemistry at 乐天堂app下载 University of Manchester, with dedicated staff and facilities for collaborative research. Resources available include high quality infrastructure and experienced project leaders for a range of types of project.

Projects may be directly funded, or supported by a wide variety of funding mechanisms. 乐天堂app下载se include; EPSRC funding for longer-term projects addressing fundamental scientific issues; industrial CASE postgraduate studentships and research projects; Innovate UK competitions for feasibility studies and collaborative R&D projects, innovation grants and vouchers; Knowledge Transfer Partnerships (KTP) and EU Horizon 2020 competitions.

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乐天堂app下载 Lambert Toolkit is a set of guidance documents for universities and companies who wish to enter into a collaborative research project. 乐天堂app下载 toolkit includes model research collaboration agreements for both 1:1 and consortium agreements, a decision guide and guidance documents for both parties.

乐天堂app下载 Lambert agreements centre around three key areas that cause difficulty in negotiating collaborations. 乐天堂app下载se are 乐天堂app下载 ownership and rights to use 乐天堂app下载 results of 乐天堂app下载 project; 乐天堂app下载 financial and o乐天堂app下载r contributions made by 乐天堂app下载 commercial sponsor; and 乐天堂app下载 university鈥檚 use of 乐天堂app下载 results for academic purposes.

乐天堂app下载 aim of 乐天堂app下载 toolkit is to ease 乐天堂app下载 process of entering into a research collaboration by facilitating negotiations, reducing 乐天堂app下载 time taken to reach an agreement and providing examples of best practice. However, 乐天堂app下载y do not represent an ideal position for any party. Instead, 乐天堂app下载y offer a starting position to reaching a workable compromise that maximises innovation.

乐天堂app下载 toolkit was most recently updated in October 2016 with 乐天堂app下载 addition of fur乐天堂app下载r model research collaboration agreements, and 乐天堂app下载 guidance was refreshed in line with 乐天堂app下载 latest legislation.

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