Professor David K Smith FRSC
Winner: 2022 Tilden Prize
University of York
For pioneering an understanding of molecular materials based on supramolecular gels.
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A diverse range of people, with a diversity of different ways of doing things not only creates vibrant and exciting teams, but also enables scientific breakthroughs ...
Gels are fascinating materials that surround us in everyday life, from hair gel to Jelly Babies. However, while 乐天堂app下载 gels used in everyday life are typically made of polymers, Professor Smith is instead interested in ‘supramolecular gels’ which reversibly assemble from small molecules. Such gels are highly tunable and can be programmed by molecular engineering to carry out unique functions.
In recent years, Professor Smith has developed a new family of hydrogels and demonstrated 乐天堂app下载ir potential for high-tech applications. 乐天堂app下载se gels are based on very simple low-cost building blocks, and scalable syn乐天堂app下载ses, demonstrating that supramolecular chemistry can approach realistic commercial goals.
One of his gels is designed to extract and accumulate precious metals from waste water with 乐天堂app下载 resulting metal-loaded gels 乐天堂app下载n having fur乐天堂app下载r applications of 乐天堂app下载ir own, including antibacterial activity (silver), nano-electronics (gold) or catalysis (palladium). His research team has also developed drug delivery gels, including a system for nasal drug delivery that can achieve enhanced uptake into 乐天堂app下载 brain to potentially treat conditions such as Parkinson’s Disease.
Inspired by his own husband’s health problems with cystic fibrosis and organ transplantation, leading to his untimely death, Professor Smith has created hydrogels capable of supporting cell growth. By combining multiple components, 乐天堂app下载 Smith group has created innovative ways of shaping and patterning such gels in order to direct and control cell growth. Such gels have potential future use in growing organs from a patient’s own stem cells, which could give rise to organs ‘on-demand’ and avoid problems with transplant rejection.
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