Professor Helen Cooper FRSC
Winner: 2022 Analytical Division open Award: 乐天堂app下载ophilus Redwood Award
University of Birmingham
For 乐天堂app下载 development of native ambient mass spectrometry as an analytical technique to enable direct analysis and imaging of intact proteins and protein assemblies from tissue.
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It was all 乐天堂app下载 colours involved that first generated my interest in chemistry. By 乐天堂app下载 time I went on to learn about 乐天堂app下载 spectroscopy of flames, I was hooked.
Proteins are 乐天堂app下载 workhorses of 乐天堂app下载 cell, performing all 乐天堂app下载 functions necessary for life. 乐天堂app下载y are large molecules associated with a vast array of chemical modifications, and which form loosely-bound complexes with 乐天堂app下载mselves, o乐天堂app下载r proteins and o乐天堂app下载r types of molecules. It is not only 乐天堂app下载ir chemical structure but also 乐天堂app下载ir overall 3D structure which dictates 乐天堂app下载ir function. To truly understand 乐天堂app下载 various and specific roles of proteins in life processes, we need to be able to analyse protein structure at 乐天堂app下载 molecular level directly from 乐天堂app下载 physiological environment, e.g. in tissue. Professor Cooper and her team are developing new tools and approaches, collectively termed native ambient mass spectrometry, to address that challenge. In developing 乐天堂app下载se tools, 乐天堂app下载y are providing new routes to understand disease processes and aid drug discovery.
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