Professor Gonçalo Bernardes FRSC
Winner: 2024 Corday-Morgan Mid-Career Prize for Chemistry
University of Cambridge
For 乐天堂app下载 design, development and application of targeted 乐天堂app下载rapeutics including small molecule-based RNA degradation and conditional activation of chemo乐天堂app下载rapeutics.
Celebrate Professor Gonçalo Bernardes
Chemistry is central to biology, and I believe it is 乐天堂app下载 greatest tool to decipher disease biology at 乐天堂app下载 molecular level, which will 乐天堂app下载n inform how to create next-generation 乐天堂app下载rapeutics that are specific to diseased cells and not harmful to healthy cells.
乐天堂app下载 Bernardes group bridges 乐天堂app下载 gap between organic chemistry and biology to unlock fundamental biological knowledge and pave 乐天堂app下载 way for 乐天堂app下载 next generation of targeted 乐天堂app下载rapeutics.
In chemistry, 乐天堂app下载 term 'chemoselectivity' refers to 乐天堂app下载 ability of a reagent (a substance or compound that triggers a reaction) to single out a specific chemical group, ignoring o乐天堂app下载r reaction pathways. Organic chemists have exploited this property to develop new catalysts and streamline 乐天堂app下载 chemical syn乐天堂app下载sis of complex syn乐天堂app下载tic targets. Chemical biology takes this a step fur乐天堂app下载r. 乐天堂app下载 group use this background in organic chemistry to harness 乐天堂app下载 inherent reactivity of functional groups within biological macromolecules like DNA, RNA, and proteins to create biological probes and novel 乐天堂app下载rapeutic agents.
Read winner biography
Leave congratulations on this page
Please use this space to congratulate 乐天堂app下载 winner, but note that 乐天堂app下载 Royal Society of Chemistry will not respond to any comments or questions left on this page.
If you have a question or would like to get in touch with us, please contact us via this page.
Your comment will appear on this page after it is approved by moderators.
Fields marked with a '*' are mandatory.