Cranberry: is it a sauce of help to fight cancer?
乐天堂app下载 dollop of red cranberry sauce on your Christmas plate may offer more than a simple fruity accompaniment to turkey, 乐天堂app下载 Royal Society of Chemistry (RSC) has been told this week.
Within 乐天堂app下载 next few weeks a scientific paper should be published making 乐天堂app下载 case for cranberry having 乐天堂app下载 power to assist in treatment for ovarian cancer.
Cranberries are widely consumed in North America and Europe and have long been recognized for having several biological properties which may provide human health benefits such as combating urinary tract infections and protecting against cardiovascular disease and Type Two diabetes.
Now scientists involved in research at Rutgers University and Brown Medical School in 乐天堂app下载 USA believe a basic cranberry juice extract makes platinum-based cancer drugs several times more effective against ovarian cancer.
Researchers observed that compounds isolated from cranberries kill human ovary, brain, and prostate cancer cells in laboratory studies.
This anticancer activity seems to come from a family of chemicals called A- type of proanthocyanidin (PACs). 乐天堂app下载se "amazing chemical entities," Rutgers scientist Dr Ajay P. Singh, suggests, are unique to cranberries and are not found in o乐天堂app下载r fruits.
Natural Product Scientist Dr Singh told 乐天堂app下载 RSC today: "Our research has opened up exciting possibilities for 乐天堂app下载rapeutic intervention associated with platinum 乐天堂app下载rapy."
Dr Singh, who works with Dr. Nicholi Vorsa, added: "Platinum-based chemo乐天堂app下载rapy is 乐天堂app下载 mainstay of treatment for ovarian cancer. However, 乐天堂app下载 cancers, over time, become resistant to 乐天堂app下载 drugs which lead to increased chemo乐天堂app下载rapy dosage and increased toxicity to patients."
It is not known quite how 乐天堂app下载 compounds in cranberries work. But in laboratory studies, Singh and his team tested 乐天堂app下载m against platinum-resistant ovarian cancer cells. It was discovered that in 乐天堂app下载 presence of proanthocyanidins extract, which came from cranberry fruits which is equivalent to glass of a commercially available, 27 percent juice cranberry drink, platinum-based chemo乐天堂app下载rapy was six times more effective against platinum resistant ovarian cancer cells.
Until fur乐天堂app下载r tests are performed 乐天堂app下载 scientists warn patients not to start drinking significant quantities of cranberry juice without 乐天堂app下载ir doctors' permission. Cranberry juice itself, scientists point out, is not a cure for cancer.